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Wood starred in 2008's Vadim Perelman-directed The Life Before Her Eyes, based on the Laura Kasischke novel of the same name, about the friendship of two teens of opposite character who are involved in a Columbine-like shooting incident at their school and are forced to make an impossible choice.
Wood played the younger version of Uma Thurman's character, Diana.
a story of a bipolar jazz musician (Michael Douglas) and his long-suffering teenage daughter, Miranda (Wood), who are reunited after his two-year stay in a mental institution and who embark on a quixotic search for Spanish treasure.
One review praised Wood's performance as "excellent".
Wood made her teenage debut as a leading film actress in 2002's Little Secrets, directed by Blair Treu, where she played aspiring 14-year-old concert violinist Emily Lindstrom.
For that role, she was nominated for Best Leading Young Actress at the Young Artist Awards.
As of 2016, she plays the sapient android Dolores Abernathy in the HBO series Westworld, for which she won a Critics' Choice Award and earned a Golden Globe and Emmy Award nomination.One critic cited her performance as "hands-down extraordinary".